Potential to Help with Depressive Episodes?
The depressive occurrences of bipolar disorder can be greatly debilitating. Could CBD oil help rebuild stability?
Knowledge surrounding mental health ailments like bipolar disorder is on the increase, but even with this progress in understanding and perception, obtaining fitting approaches to treatment can be tricky. While it is more widely recognized for its pain-relieving, anti-inflammatory qualities, CBD oil is now being examined for its possible benefits for managing mood disturbances.
Described by periodic peaks and dips of intense moods described as manic and depressive episodes, bipolar disorder will affect 4.4% of people in their lifetimes. While manic incidents can be followed by inappropriate actions, impulsive reactions, and insomnia, depressive episodes can make the victim exhibiting hopelessness, worthlessness, and possibly suicidal.
The most well-known approaches to bipolar therapy include pharmaceuticals, but adopting CBD oil for bipolar disorder may be worth investigating.
Effectiveness of CBD Oil for Bipolar Disorder
There are no clinical trials on the links between bipolar disorder and the use of cannabinoids. But a review on the topic suggested that based on what we do know, “cannabidiol (CBD) may exert sedative, hypnotic, anxiolytic, antidepressant, antipsychotic and anticonvulsant effects.”
Already identified to elevate mood and reduce depression, CBD oil may also be used to manage bipolar disorder’s performance by its impacts on the endocannabinoid system. Elements like tetrahydrocannabinol (THC) and cannabidiol (CBD), are the plant version of the endocannabinoids naturally produced by your body’s endocannabinoid system. Cannabinoids, whether created by cannabis or your body, can affect CB1 and CB2 receptors directly and indirectly.
Various investigations have connected changes in the endocannabinoid system with mental health, implying that CBD oil may support. One such study was carried out in Italy that studied the CB1 receptor in patients who had extreme depression or bipolar disorder and a healthy test group. While the outcomes were not notable enough to draw a conclusive result, the study stated that variations in the endocannabinoid system “may contribute to the susceptibility to mood disorders.” CBD acts in a way that elevates the amount of endocannabinoid in the system to attain homeostasis, which could give a stronger mental state.
Further studies on animal populations have connected a defective endocannabinoid system to reduced serotonin levels, and it is also believed that low serotonin levels are linked to bipolar disorder. CBD can possibly raise serotonin levels in the brain by acting on the 5-HT1A serotonin receptor. By this procedure, CBD oil could be beneficial for addressing specific mood disturbances by restoring the endocannabinoid system and reducing the depressive signs of bipolar disorder.
Regrettably, CBD did not present the same encouraging influence on manic episodes.
In one review, researchers investigated the outcomes of CBD on two sufferers with bipolar affective disorder. Both bipolar patients were administered a placebo for the first five days of the investigation and CBD for days 6-30. On days 6-20, the first patient was additionally given a dose of olanzapine. On day 31, CBD was stopped, and both were given a placebo for five more days. The first patient, who was also administered olanzapine, showed a positive change in her symptoms while using both medicines and encountered no improvement during the placebo and CBD tests. The second patient experienced no symptom changes.
So, CBD oil may hold the most significant potential for managing the depressive faction of manic depressive fluctuations.
How can CBD Oil help Bipolar Episodes?
Sadly, most medications for bipolar disorder are not sufficient. While prescription medicines, combined with psychotherapy, can help a large number of people, many others find their condition is resistant to medication.
While CBD oil is obtaining traction in medical sets for its use in treating mental illness. The most common medicines prescribed to patients with bipolar disorder are still antidepressants, mood stabilizers, and antimanic drugs.
Analysis has revealed that antidepressants can raise the probability of mania and accelerated cycling, which is why mood stabilizers are often prescribed in combination with these medicines. While effective for some, this cocktail of medications leaves others with a host of additional side effects to contend with on top of their condition, as outlined in the chart below.
If you’re contemplating combining CBD oil to your bipolar medication, you must talk to your GP and follow the potential drug interactions shown in the table below in mind.
|Commonly Prescribed Medication for Bipolar Disorder||Possible Side Effects||Possible Side Effects of Combining CBD Oil + Medication for Bipolar Disorder|
|Lithium||Blurred vision, difficulty walking, nausea, shaking hands, dry mouth, dizziness and drowsiness, stomach pains, vomiting.||Possible increase in drowsiness, confusion and fatigue.|
|Olanzapine||Muscle spasms, dizziness and fatigue. Increase in weight as well as higher cholesterol. Dry mouth.||Possible increase in drowsiness, confusion and fatigue.|
|Quetiapine||Headaches, dizziness low blood pressure when standing up. Drowsiness, Dry mouth, fatigue constipation.||Possible increase in drowsiness, confusion and fatigue.|
|Ziprasidone||Nausea and stomach upset. Diarrhoea or constipation. Cough, cold flu like symptoms, tremors.||Possible increase in drowsiness, confusion and fatigue.|
|Lurasidone||Drowsiness and dizziness. Pain when moving, weight gain, involuntary body movements.||Possible increase in drowsiness, confusion and fatigue.|
|Aripiprazole||Involuntary body movements including tremors and spasms. Difficulty swallowing, mood swings, fainting or restlessness.||Possible increase in drowsiness, confusion and fatigue.|
|Valproate||Drowsiness, Confusion and change in mental state, Bruising, Vomiting, Bleeding from mouth or nose or feeling cold.||Could increase risk of damage to the liver.|
|Symbyax||Increased appetite and weight gain. Diarrhoea or constipation, dry mouth, dizziness, fatigue.||Could experience confusion, fatigue, dizziness.|
|Risperidone||Weight gain, dizziness, drowsiness, fatigue, muscle spasms, feelings of being hot or cold.||Possible increase in drowsiness, confusion and fatigue.|
This why we always stress you should consult your GP before trying CBD products.
Taking CBD Oil for Bipolar Disorder.
If you’re unsatisfied with the way you are managing your bipolar disorder, it is worth talking to a medical expert to see if CBD oil could help.
While it is commonly well tolerated, CBD oil can interact with some medicines, including antidepressants, so you must first seek medical advice.
CBD Oil Dosage for Bipolar Disorder
There is no one measurement fits all answer when it comes to CBD oil dosages. What serves for one person will not be what works for another. We recommend starting with the lowest recommended dose for your CBD oil product and slowly building on the dosage if required.